Antimicrobial Matrix with Lidocaine

PRO-1041-US-EN-v3

Microlyte® PainGuard

Reducing infection risk and pain with one solution

A synthetic antimicrobial matrix containing ionic and metallic silver at low, non-toxic levels — providing a 99.99% reduction of a broad range of microbes on the matrix while releasing a uniform, unit-dose of lidocaine HCl for simultaneous pain relief.

99.99%MICROBE REDUCTION
Silver + Lidocaine

Two Solutions, One Matrix

Infection Risk Reduction Meets Pain Relief

Microlyte® PainGuard™ pairs broad-spectrum antimicrobial silver with a uniform unit-dose of lidocaine in a single, conformable matrix.

99.99%

Microbe reduction

Reduction of a broad range of microbes on the matrix from ionic and metallic silver (in vitro).

>80%

Lidocaine release

More than 80% of lidocaine HCl released within the first 30 minutes of application.

Unit-dose

Lidocaine delivery

Releases a uniform, unit-dose of lidocaine HCl for simultaneous pain relief.

Resorbable

Synthetic matrix

Thin, porous matrix of resorbable polymers designed to mimic human ECM.

Engineered to Mimic Human ECM

A synthetic, thin, porous matrix made of resorbable polymers, designed to conform with transparency to the microtextures of the wound bed.

1

Conforms with Transparency

Conforms with transparency to the microtextures of the wound bed for clear visualization and contact.

2

Synthetic Porous Matrix

A synthetic, thin, porous matrix made of resorbable polymers, designed to mimic human ECM.

3

Designed for Pain Relief

More than 80% release of lidocaine HCl within the first 30 minutes to assist in pain relief.

Available Sizes

Three sizes deliver a uniform unit-dose of lidocaine HCl scaled to wound coverage.

SizeSKUWound CoverageLidocaine / Piece
3 × 3 cmI-MLPG03039 cm²3.6 mg
5 × 5 cmI-MLPG050525 cm²10 mg
10 × 10 cmI-MLPG1010100 cm²40 mg

References & Clearance

Microlyte® PainGuard™ is supported by data on file and FDA 510(k) clearance.

1

Microlyte Shelf Life and Stability

Data on file, Imbed Biosciences

2

Measurement of Antimicrobial Activity of Microlyte Ag

Data on file, Imbed Biosciences

3

Surfaces modified with nanometer-thick silver impregnated polymeric films that kill bacteria but support growth of mammalian cells

Agarwal A, et al. (2010)

Biomaterials. 2010;31(4):680-90.

4

Product Handleability Evaluation Report

Data on file, Imbed Biosciences

5

Systemic Toxicity, Local Tissue Response, and Wound Healing Study of Microlyte Ag Following Repeated Treatment to Full-Thickness Wounds in Rats – 28 Days

Data on file, Imbed Biosciences

6

510(k) Summary K211943: Microlyte Ag/Lidocaine

U.S. Food and Drug Administration (2021)

FDA.gov. Published July 2021.

† As demonstrated in vitro.

Document Reference: PRO-1041-US-EN-v3Manufactured by Imbed Biosciences · Distributed by BioLab Holdings

Reduce Infection Risk. Relieve Pain.

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